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pentobarbital will reduce the level or influence of atogepant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Advisable atogepant dosage with concomitant use of solid or moderate CYP3A4 inducers is thirty mg or sixty mg qDay.​​​​​​​​​​​​​​​​​​​​​​​​​​â